Invention Grant
- Patent Title: Triazolotriazine derivatives as A2A receptor antagonists
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Application No.: US17255451Application Date: 2018-06-26
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Publication No.: US11858942B2Publication Date: 2024-01-02
- Inventor: Sanxing Sun , Jinqi Ye , Long Zhao , Chongbo Hu , Zhengshu Chen
- Applicant: ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD.
- Applicant Address: CN Zhejiang
- Assignee: ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD.
- Current Assignee: ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD.
- Current Assignee Address: CN Zhejiang
- Agency: Honigman LLP
- Agent Thomas A. Wootton, Esq.; Jonathan P. O'Brien
- International Application: PCT/IB2018/054690 2018.06.26
- International Announcement: WO2020/002968A 2020.01.02
- Date entered country: 2020-12-23
- Main IPC: C07D519/00
- IPC: C07D519/00 ; A61P35/00 ; A61K31/53 ; C07D487/04
Abstract:
The present invention provides triazolotriazine derivatives of formula (1) as A2A receptor antagonists. Compounds of formula (1) and pharmaceutical compositions including the compounds can be used for the treatment of disorders related to A2A receptor hyperfunctioning, such as certain types cancers. Compounds of formula (1) and methods of preparing the compounds are disclosed in the invention.
Public/Granted literature
- US20210292334A1 TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS Public/Granted day:2021-09-23
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