Invention Grant
- Patent Title: Heterodimeric antibodies that bind CD3 and GPC3
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Application No.: US17692045Application Date: 2022-03-10
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Publication No.: US11859012B2Publication Date: 2024-01-02
- Inventor: Alex Nisthal , Nargess Hassanzadeh-Kiabi , Katrina Bykova , Matthew J. Bernett , Rajat Varma
- Applicant: Xencor, Inc.
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Pasadena
- Agency: Morgan, Lewis & Bockius, LLP
- Agent Louis-Vu T. Nguyen; Christopher J. Betti
- Main IPC: C07K16/46
- IPC: C07K16/46 ; C07K16/28 ; A61K39/00 ; A61P35/00
Abstract:
Provided herein are novel GPC3 binding domains, and antibodies that include such GPC3 binding domains (e.g., anti-GPC3×anti-CD3). Also provided herein are methods of using such antibodies for the treatment of GPC3-associated cancers.
Public/Granted literature
- US20220306767A1 HETERODIMERIC ANTIBODIES THAT BIND CD3 AND GPC3 Public/Granted day:2022-09-29
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