A three-dimensional dynamic and static load test system for simulating deep roadway excavation and a method thereof are provided, which relates to the technical field of indoor simulation testing in underground engineering. The system includes a mobile platform, a box body, a support frame, a roadway excavation device, and a data monitoring unit. The system and method of the disclosure can reproduce the whole process of roadway excavation, simulate the multi-directional loading of deep roadway, and restore the real stress state of deep roadway under the influence of dynamic and static load superimposed disturbance. The problem of insufficient research under the condition of unidirectional static loading and lack of multi-directional dynamic and static loading in current large-scale experimental devices has been solved, and the stress and deformation of the surrounding rock of the roadway are reflected in real-time through the data monitoring unit.