Invention Grant
- Patent Title: Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors
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Application No.: US17730438Application Date: 2022-04-27
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Publication No.: US11866418B2Publication Date: 2024-01-09
- Inventor: Pravin L. Kotian , Yarlagadda S. Babu , Weihe Zhang , Peng-Cheng Lu , Minwan Wu , Wei Lv , Trung Xuan Nguyen , Zhao Dang , Venkat R. Chintareddy , V. Satish Kumar , Krishnan Raman
- Applicant: BioCryst Pharmaceuticals, Inc.
- Applicant Address: US NC Durham
- Assignee: BioCryst Pharmaceuticals, Inc.
- Current Assignee: BioCryst Pharmaceuticals, Inc.
- Current Assignee Address: US NC Durham
- Agency: Foley Hoag LLP
- Agent Dana M. Gordon; Laura A. Wzorek
- The original application number of the division: US17202965 2021.03.16
- Main IPC: C07D401/10
- IPC: C07D401/10 ; C07D209/12 ; C07D261/20 ; C07D307/80 ; C07D333/64 ; C07D401/12 ; C07D405/10

Abstract:
Disclosed are compounds of formulae I and II, and pharmaceutically acceptable salts and prodrugs thereof, which are inhibitors of the complement system. Also provided are pharmaceutical compositions comprising such a compound, and methods of using the compounds and compositions in the treatment or prevention of a disease or condition characterized by aberrant complement system activity.
Public/Granted literature
- US20230099716A1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS Public/Granted day:2023-03-30
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