Invention Grant
- Patent Title: Modulators of Cystic Fibrosis Transmembrane Conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulators
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Application No.: US17323267Application Date: 2021-05-18
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Publication No.: US11866450B2Publication Date: 2024-01-09
- Inventor: Jeremy J. Clemens , Alexander Russell Abela , Corey Don Anderson , Brett B. Busch , Weichao George Chen , Thomas Cleveland , Timothy Richard Coon , Bryan Frieman , Senait G. Ghirmai , Peter Grootenhuis , Anton V. Gulevich , Sara Sabina Hadida Ruah , Clara Kuang-Ju Hsia , Ping Kang , Haripada Khatuya , Jason McCartney , Mark Thomas Miller , Prasuna Paraselli , Fabrice Pierre , Sara E. Swift , Andreas Termin , Johnny Uy , Carl V. Vogel , Jinglan Zhou
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- The original application number of the division: US16276350 2019.02.14
- Main IPC: C07D513/22
- IPC: C07D513/22 ; A61K31/439 ; A61P11/00 ; A61K31/47 ; A61K31/404 ; C07D515/22
Abstract:
Compounds of Formula (I):
pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.
pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.
Public/Granted literature
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