A data transmission circuit and method, and a storage device are provided. The data transmission circuit includes a serial-parallel conversion module, a comparison module, a data conversion module and a write circuit module. The serial-parallel conversion module receives a plurality of pieces of external data in batches and outputs initial parallel data according to the external data. The comparison module compares the received initial parallel data with global data to output a comparison result. The data conversion module, responsive to that the comparison result indicates that the preset threshold is exceeded, inverts the initial parallel data and transmits the inverted data to a data bus, and responsive to that the comparison result indicates that the preset threshold is not exceeded, transmits the initial parallel data to the data bus. The write circuit module transmits data on the data bus to a global data bus.