The present invention provides a detection circuit for a connection impedance and an electronic device. The detection circuit includes: a detection operational amplifier module, wherein the detection operational amplifier module includes: a first buffer, a switch unit, and a main operational amplifier; a first input terminal of the first buffer is connected to a first acquisition electrode through a first front-end circuit, an output terminal of the main operational amplifier is connected to a back-end circuit, and an output terminal of the first buffer is connected to a second input terminal of the first buffer; a first terminal of the switch unit is directly or indirectly connected to the first front-end circuit, and a second terminal of the switch unit is connected to the back-end circuit; and the switch unit is configured to: control the first front-end circuit to be directly connected to the back-end circuit, to form a straight-through channel.