Invention Grant
- Patent Title: Method of treating spinal cord injury
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Application No.: US16956935Application Date: 2018-12-19
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Publication No.: US11883469B2Publication Date: 2024-01-30
- Inventor: Pradeep Kumar , Viness Pillay , Yahya Essop Choonara , Girish Modi
- Applicant: UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG
- Applicant Address: ZA Johannesburg
- Assignee: UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG
- Current Assignee: UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG
- Current Assignee Address: ZA Johannesburg
- Agency: LADAS & PARRY LLP
- Priority: ZA 201708733 2017.12.21
- International Application: PCT/IB2018/060345 2018.12.19
- International Announcement: WO2019/123317A 2019.06.27
- Date entered country: 2020-06-22
- Main IPC: A61K38/39
- IPC: A61K38/39 ; A61K47/58 ; A61K47/64 ; A61P25/00 ; A61K9/00 ; A61K9/70 ; A61K47/18 ; A61L27/18 ; A61L27/22 ; A61L27/24 ; A61L27/56

Abstract:
A polyacrylonitrile (PANi) based pharmaceutical composition providing a porous implant for use in treating spinal cord trauma and/or spinal cord injury. Particularly a pharmaceutical composition including polyacrylonitrile (PANi) and/or elastin (E) and/or collagen (C) to form a PANi-E and/or PANi-C and/or a PANi-EC polymer network. Particularly, a pharmaceutical composition including polyacrylonitrile (PANi), elastin (E), and collagen (C) together forming a polyacrylonitrile (PANi), elastin (E), collagen (C) polymer network (PANi-E-C), wherein the polyacrylonitrile (PANi) may be crosslinked to form a crosslinked interpenetrating polyacrylonitrile (PANi), elastin (E) and collagen (C) polymer network (xpi-PANi-E-C), and wherein secondary protein structures of elastin (E) and collagen (C) reorientate. The disclosure extends to use of the pharmaceutical composition in the treatment of spinal cord trauma and/or spinal cord injury.
Information query
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