- Patent Title: Gonadotropin releasing hormone receptor antagonist and use thereof
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Application No.: US17920029Application Date: 2021-05-20
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Publication No.: US11884636B2Publication Date: 2024-01-30
- Inventor: Guoqiang Liu , Wei Liu , Yandong Wang
- Applicant: SHIJIAZHUANG YILING PHARMACEUTICAL CO., LTD.
- Applicant Address: CN Hebei
- Assignee: SHIJIAZHUANG YILING PHARMACEUTICAL CO., LTD.
- Current Assignee: SHIJIAZHUANG YILING PHARMACEUTICAL CO., LTD.
- Current Assignee Address: CN Shijiazhuang Hebei Province
- Agency: Global IP Services
- Agent Tianhua Gu
- Priority: CN 2010311436.8 2020.04.20
- International Application: PCT/CN2021/094748 2021.05.20
- International Announcement: WO2021/213538A 2021.10.28
- Date entered country: 2022-10-20
- Main IPC: C07D239/54
- IPC: C07D239/54 ; A61P5/26 ; A61K31/513 ; A61P5/02 ; A61P5/24 ; A61P15/08
Abstract:
The present invention provides a compound or a pharmaceutically acceptable salt, isomer, prodrug, polymorph or solvate thereof, and a preparation method therefor and use thereof. The compound provided in the present invention has comparable or superior activity to Elagolix as a GnRHR antagonist in calcium flux assays and have better pharmacokinetic properties.
Public/Granted literature
- US20230144828A1 GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONIST AND USE THEREOF Public/Granted day:2023-05-11
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