![Crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra- hydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof](/docs/US/2024-01-30/US11884674B2/abs.jpg.600x600.jpg)
- Patent Title: Crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra- hydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof
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Application No.: US17858826Application Date: 2022-07-06
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Publication No.: US11884674B2Publication Date: 2024-01-30
- Inventor: Zhiwei Wang , Yunhang Guo , Gongyin Shi , Lai Wang
- Applicant: BEIGENE SWITZERLAND GMBH
- Applicant Address: CH Basel
- Assignee: BEIGENE SWITZERLAND GMBH
- Current Assignee: BEIGENE SWITZERLAND GMBH
- Current Assignee Address: CH Basel
- Agency: COOLEY LLP
- Priority: WO TCN2016095510 2016.08.16
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61P35/02 ; A61P35/04
![Crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra- hydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof](/abs-image/US/2024/01/30/US11884674B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to a crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide for inhibiting Btk, methods of preparation thereof and pharmaceutical compositions, and use of the crystalline form above in the treatment of a disease, or in the manufacturing of a medicament for the treatment of a disease.
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