Invention Grant
- Patent Title: 3H,4H,5H,6H,7H-pyrimido[4,5-b][1,4]oxazine-4,6-dione derivatives as TRPA1 inhibitors
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Application No.: US17719430Application Date: 2022-04-13
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Publication No.: US11884681B2Publication Date: 2024-01-30
- Inventor: Martin Thomas Fleck , Florian Paul Christian Binder
- Applicant: Boehringer Ingelheim International GmbH
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Philip I. Datlow
- Priority: EP 168440 2021.04.14
- Main IPC: C07D498/04
- IPC: C07D498/04
![3H,4H,5H,6H,7H-pyrimido[4,5-b][1,4]oxazine-4,6-dione derivatives as TRPA1 inhibitors](/abs-image/US/2024/01/30/US11884681B2/abs.jpg.150x150.jpg)
Abstract:
The present disclosure provides certain 3H,4H,5H,6H,7H-pyrimido[4,5-b][1,4]oxazine-4,6-dione derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.
Public/Granted literature
- US20220340593A1 3H,4H,5H,6H,7H-PYRIMIDO[4,5-B][1,4]OXAZINE-4,6-DIONE DERIVATIVES AS TRPA1 INHIBITORS Public/Granted day:2022-10-27
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