Invention Grant
- Patent Title: Anti-IL-36 antibodies and methods of use thereof
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Application No.: US16720541Application Date: 2019-12-19
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Publication No.: US11884719B2Publication Date: 2024-01-30
- Inventor: Chingwei Vivian Lee , Germaine Fuh-Kelly , Louise Scharf , Tina Thai , Ashka Bharat Patel , Shashank Bharill , Erik Edward Karrer
- Applicant: 23andMe, Inc.
- Applicant Address: US CA Sunnyvale
- Assignee: 23andMe, Inc.
- Current Assignee: 23andMe, Inc.
- Current Assignee Address: US CA Sunnyvale
- Agency: FisherBroyles, LLP
- Agent Adam K. Whiting
- Main IPC: C07K16/24
- IPC: C07K16/24 ; C07K16/46 ; A61P29/00 ; A61K38/00

Abstract:
The present invention provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human IL-36 cytokines, IL-36α, IL-36β, and/or IL-36γ, and block the IL-36 stimulated signaling pathways. Compositions comprising such binding proteins and methods of making and using such binding proteins are also provided.
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