Invention Grant
- Patent Title: Method of inactivating a glucocorticoid receptor gene in an isolated cell
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Application No.: US17127210Application Date: 2020-12-18
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Publication No.: US11884930B2Publication Date: 2024-01-30
- Inventor: Andreas Reik , Michael Jensen , Michael C. Holmes , Philip D. Gregory , Dale Ando
- Applicant: Sangamo Therapeutics, Inc. , City of Hope
- Applicant Address: US CA Brisbane
- Assignee: Sangamo Biosciences, Inc.,City of Hope
- Current Assignee: Sangamo Biosciences, Inc.,City of Hope
- Current Assignee Address: US CA Brisbane; CA California
- Agency: Foley & Lardner LLP
- The original application number of the division: US14947476 2015.11.20
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N15/86 ; C12N15/62 ; C07K14/72 ; C12N9/22 ; G01N33/74
Abstract:
Disclosed herein are methods and compositions for inactivation of the human glucocorticoid receptor (GR) gene by targeted cleavage of genomic DNA encoding the GR. Such methods and compositions are useful, for example, in therapeutic applications which require retention of immune function during glucocorticoid treatment.
Public/Granted literature
- US20210102222A1 METHOD OF INACTIVATING A GLUCOCORTICOID RECEPTOR GENE IN AN ISOLATED CELL Public/Granted day:2021-04-08
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