A high-strength steel sheet includes a chemical composition including: by mass %, C: 0.080 to 0.500%, Si: 2.50% or less, Mn: 0.50 to 5.00%, P: 0.100% or less, S: 0.0100% or less, Al: 0.001 to 2.500%, N: 0.0150% or less, O: 0.0050% or less, and the balance: Fe and inevitable impurities. The high-strength steel sheet satisfying a predetermined formula has a microstructure in a region from ⅛t to ⅜t from a steel sheet surface. The microstructure includes: by volume %, 20% or more of acicular ferrite, 20% or more of an island-shaped hard structure including residual austenite, 2% to 25% of residual austenite, and 20% or less of aggregated ferrite.