Invention Grant
- Patent Title: Method for depleting malignant T-cells
-
Application No.: US17832225Application Date: 2022-06-03
-
Publication No.: US11885806B2Publication Date: 2024-01-30
- Inventor: Martin Pulé , Paul Maciocia
- Applicant: AUTOLUS LIMITED
- Applicant Address: GB London
- Assignee: AUTOLUS LIMITED
- Current Assignee: AUTOLUS LIMITED
- Current Assignee Address: GB London
- Agency: MARSHALL, GERSTEIN & BORUN LLP
- Priority: GB 03905 2014.03.05 GB 16908 2014.09.25
- Main IPC: G01N33/574
- IPC: G01N33/574 ; G16H50/30 ; C12Q1/6886 ; C12Q1/686 ; A61K39/00
Abstract:
The present invention relates to a chimeric antigen receptor (CAR) which comprises an antigen-binding domain which selectively binds TCR beta constant region 1 (TRBC1) or TRBC2; cells; such a T cells comprising such a CAR; and the use of such cells for the treatment of a T-cell lymphoma or leukaemia in a subject.
Public/Granted literature
- US20230019650A1 METHODS Public/Granted day:2023-01-19
Information query
IPC分类:
