A system and method of configuring monitor blocks and effect blocks associated with a process control system for a process plant includes causing a display device to display a graphical user interface, the graphical user interface indicating a first monitor block, a second monitor block, and an effect block. The system and method further includes enabling a user to input configuration data via the input device, including: (i) configuring one of the outputs of the first monitor block to serve as one of the inputs of the second monitor block, (ii) configuring an additional one of the outputs of the first monitor block and one of the outputs of the second monitor block to serve as inputs to the effect block, and (iii) designating at least one of the plurality of cells of each of the first monitor block, the second monitor block, and the effect block as a trigger associated with the respective input/output pair for the respective cell and corresponding to a condition in the process plant.