A processor configured for real-time transaction processing is disclosed. A processor circuit includes configuration registers that designate a first range of physical memory addresses as reserved for real-time memory requests and a second, non-overlapping range of physical memory addresses that are shared between real-time and non-real-time memory requests. In response to determining that a memory request is associated with an address in the first range, the processor tags the request as a real-time request. The configuration registers may also store information designating portions of one or more cache memories and one or more buffers as being reserved for real-time memory requests. During arbitration, real-time memory requests are given priority over older, non-real-time memory requests.