A method for executing computation, a computing device, a computing system, and a storage medium are provided. The method includes: confirming, via a compiler, whether there is a call instruction related to a thread block modification request in a kernel function to be compiled; in response to confirming that there is the call instruction related to the thread block modification request in the kernel function to be compiled, determining a corresponding program segment associated with the call instruction; configuring a required thread block and thread local register for the corresponding program segment; and inserting a control instruction into the corresponding program segment to enable the thread block configured for the corresponding program segment to execute relevant computation of the corresponding program segment, and an unconfigured thread block not to execute the relevant computation. The disclosure can improve overall performance, make coding and maintenance easy and reduce error rate of code.