Intelligent file-level validation is described. A service provider (e.g., an administrator) can determine rule(s) based partly on specified data. The service provider can receive a data file. The service provider can determine modification data that indicates an amount of change to result from modifying previously stored data based on the data file, and can analyze the modification data based partly on threshold(s) associated with the rule(s). Each threshold can indicate an amount of change that is determined to be permissible for the data file, for the corresponding rule. The service provider can determine whether the data file is valid based partly on analyzing the modification data in view of the rule(s). Valid data files can be stored in a database that represents a source of truth and invalid data files can be routed to error handling.