A pixel drive circuit includes: a driving compensation circuitry, a data-writing circuitry, and a flip-elimination circuitry. By configuring the flip-elimination circuitry, the reference voltage can be written to the control end of the drive transistor through the independent circuit line in the compensation phase, thereby it is unnecessary to write the reference voltage through the data-voltage line before each writing of the data voltage. In the writing phase of the data voltage, the entire time of each writing can be used for the writing of data voltage without reserving half of the time for writing the reference voltage, so that the level switch frequency of the data line does not need to reach twice the normal light-emitting frequency, which reduces the burden on the display panel, greatly reduces the power consumption of the screen, and improves product competitiveness.