Provided are a device and a method for transmitting and receiving voice data in a wireless communication system. A method for operating a transmission terminal for transmitting a voice signal comprises the steps of: generating sampling and bitrate request information including sampling information for determining a sampling rate of the voice signal and bitrate information for determining a bitrate of the voice signal, and transmitting the generated sampling and bitrate request information to a reception terminal; receiving, from the reception terminal, combined determination information obtained by at least one combination of the sampling rate determined on the basis of the sampling information and the bitrate determined on the basis of the bitrate information; and compressing the voice signal according to the received combined determination information, and transmitting the compressed voice signal to the reception terminal.