A method and device of transparency processing of music. The method comprises: obtaining a characteristic of a music to be played; inputting the characteristic into a transparency probability neural network to obtain a transparency probability of the music to be played; determining a transparency enhancement parameter corresponding to the transparency probability, the transparency enhancement parameter is used to perform transparency adjustment on the music to be played. The present invention constructs a transparency probability neural network in advance based on deep learning and builds a mapping relationship between the transparency probability and the transparency enhancement parameters can be constructed, so that the music to be played can be automatically permeated.