Systems and methods for duplexer circuits having signal leakage cancellation are provided. In one aspect, a duplexer circuit includes a transmit path splitter configured to split a radio frequency transmit signal into a pair of radio frequency transmit signals, and a receive path splitter configured to combine a pair of radio frequency receive signals. The duplexer circuit also includes an antenna path splitter configured to combine a pair of radio frequency transmit signals and split a radio frequency receive signal into the pair of radio frequency receive signals, and first and second duplexers. The first duplexer is coupled to a first leg of each of the transmit path splitter, the receive path splitter, and the antenna path splitter, and the second duplexer is coupled to a second leg of each of the transmit path splitter, the receive path splitter, and the antenna path splitter.