Disclosed is an image sensing device and an operating method thereof. The image sensing device may include an analyzer suitable for analyzing a state of each of multiple kernels based on system information and a plurality of pixel values, a detector suitable for detecting color noise of a target pixel value among pixel values included in a target kernel among the multiple kernels, according to the analysis result of the analyzer, and a corrector suitable for correcting the target pixel value according to the detection result of the detector.