The present invention provides a method to consistently and continuously monitor an individual's ocular fundus via the acquisition of standardized fundus images longitudinally, especially for (but not limited to) individuals with diabetic retinopathy. Briefly, the key points of the present invention include: (a) using an aiming beam to target anatomic landmarks of the ocular fundus; (b) using normal anatomic landmarks as registration points; (c) providing a method of image acquisition to create standardized images.