Invention Grant
- Patent Title: Compounds for use in inducing myocardial perfusion recovery
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Application No.: US17309720Application Date: 2019-12-20
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Publication No.: US11890324B2Publication Date: 2024-02-06
- Inventor: Anette Sams Nielsen , Lars Ingvar Herbert Edvinsson
- Applicant: Epoqe Pharma ApS
- Applicant Address: DK Copenhagen N
- Assignee: Epoqe Pharma ApS
- Current Assignee: Epoqe Pharma ApS
- Current Assignee Address: DK Copenhagen N
- Agency: Grüneberg and Myers PLLC
- Priority: SE 516526 2018.12.21
- International Application: PCT/SE2019/051333 2019.12.20
- International Announcement: WO2020/130927A 2020.06.25
- Date entered country: 2021-06-16
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61P9/08 ; A61P9/00 ; A61P9/10 ; A61K38/22 ; A61K45/06

Abstract:
A calcitonin gene-related peptide (CGRP) compound can be selected from N-alpha-[2-(2-{2-[(S)-4-carboxy-4-(17-carboxyheptadecanoylamino)-butyrylamino]ethoxy}ethoxy)acetyl][Ser1]alpha-human CGRP peptide (α-CGRP-analogue), or derivatives thereof; or N-alpha-[2-(2-{2-[(S)-4-carboxy-4-(17-carboxyheptadecanoylamino)butyryl-amino]-ethoxy}ethoxy)acetyl][Ser1]beta-human CGRP peptide (β-CGRP-analogue), or derivatives thereof. The CGRP compound can be used to induce myocardial perfusion recovery, in connection with AMI, by activating any CGRP family of receptors with a larger CGRP compound: CGRP potency ratio in the coronary artery than in the mesenteric artery.
Public/Granted literature
- US20220031809A1 COMPOUNDS FOR USE IN INDUCING MYOCARDIAL PERFUSION RECOVERY Public/Granted day:2022-02-03
Information query
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