Invention Grant
- Patent Title: Amidated peptides and their deamidated counterparts displayed by non-HLA-a*02 for use in immunotherapy against different types of cancers
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Application No.: US17489446Application Date: 2021-09-29
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Publication No.: US11891427B2Publication Date: 2024-02-06
- Inventor: Jens Hukelmann , Heiko Schuster , Lena Wullkopf , Christoph Schraeder , Jens Fritsche , Daniel Johannes Kowalewski , Michael Roemer , Oliver Schoor
- Applicant: Immatics Biotechnologies GmbH
- Applicant Address: DE Tuebingen
- Assignee: IMMATICS BIOTECHNOLOGIES GMBH
- Current Assignee: IMMATICS BIOTECHNOLOGIES GMBH
- Current Assignee Address: DE Tuebingen
- Agency: McBee Moore & Vanik IP, LLC
- Main IPC: C07K14/725
- IPC: C07K14/725 ; A61K35/17 ; C07K14/74 ; C07K16/28 ; A61K38/00

Abstract:
The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 113, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.
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