Invention Grant
- Patent Title: Compositions and methods for treating age-related diseases
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Application No.: US16956339Application Date: 2018-12-21
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Publication No.: US11891442B2Publication Date: 2024-02-06
- Inventor: Anton Wyss-Coray , John Vincent Pluvinage , Michael C. Bassik , Michael Haney , Benjamin Smith , Carolyn Bertozzi
- Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
- Applicant Address: US CA Stanford
- Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY,THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
- Current Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY,THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
- Current Assignee Address: US CA Stanford; US DC Washington
- Agency: Casimir Jones, S.C.
- Agent Kirk J. Hogan
- International Application: PCT/US2018/067250 2018.12.21
- International Announcement: WO2019/126725A 2019.06.27
- Date entered country: 2020-06-19
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61P25/28 ; A61K39/395 ; A61K39/00 ; A61K38/47 ; C12N9/24 ; A61K47/68 ; A61M25/00

Abstract:
Provided herein are compositions, methods, kits and systems for treating cells, tissues and subjects to alter age-related biology (e.g., to study or to treat age-related diseases and conditions). In particular, provided herein are compositions, methods, and uses for inhibition or modification of sialic acid or its cognate receptor to restore phagocytosis in aged cells.
Public/Granted literature
- US20200317778A1 COMPOSITIONS AND METHODS FOR TREATING AGE-RELATED DISEASES Public/Granted day:2020-10-08
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