Invention Grant
- Patent Title: Production of T cell retargeting hetero-dimeric immunoglobulins
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Application No.: US16931506Application Date: 2020-07-17
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Publication No.: US11891454B2Publication Date: 2024-02-06
- Inventor: Stanislas Blein , Romain Ollier , Darko Skegro , Samuel Hou
- Applicant: Ichnos Sciences SA
- Applicant Address: CH La Chaux-de-Fonds
- Assignee: Ichnos Sciences SA
- Current Assignee: Ichnos Sciences SA
- Current Assignee Address: CH La Chaux-de-Fonds
- Agency: STERNE, KESSLER, GOLDSTEIN & FOX P.L.L.C.
- Priority: EP 191386 2013.11.04
- Main IPC: C07K16/46
- IPC: C07K16/46 ; C07K16/28 ; C07K16/32 ; C07K16/42
Abstract:
The present invention describes hetero-dimeric immunoglobulins or fragments thereof which bind to CD3 and a disease associated antigen. These hetero-dimeric immunoglobulins have been engineered to promote hetero-dimer formation during expression and can be purified to a high degree using a Protein A differential purification technique.
Public/Granted literature
- US20210171661A1 PRODUCTION OF T CELL RETARGETING HETERO-DIMERIC IMMUNOGLOBULINS Public/Granted day:2021-06-10
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