Invention Grant
- Patent Title: Transgene cassettes designed to express a human MECP2 gene
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Application No.: US17112299Application Date: 2020-12-04
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Publication No.: US11891616B2Publication Date: 2024-02-06
- Inventor: Steven J. Gray , Sarah Sinnett
- Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: Board of Regents of the University of Texas System
- Current Assignee: Board of Regents of the University of Texas System
- Current Assignee Address: US TX Austin
- Agency: DLA Piper LLP US
- Main IPC: C12N15/86
- IPC: C12N15/86 ; C12N15/113
Abstract:
The present disclosure provides methods and compositions for the treatment of diseases and genetic disorders linked to MeCP2 loss and/or misfunction, including RETT syndrome. The methods and compositions of the present disclosure comprise rAAV vectors and rAAV viral vectors comprising transgene nucleic acid molecules comprising nucleic acid sequences encoding for a MeCP2 polypeptide.
Public/Granted literature
- US20210180085A1 TRANSGENE CASSETTES DESIGNED TO EXPRESS A HUMAN MECP2 GENE Public/Granted day:2021-06-17
Information query
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