Invention Grant
- Patent Title: RPE cell populations and methods of generating same
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Application No.: US15539473Application Date: 2015-12-30
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Publication No.: US11891622B2Publication Date: 2024-02-06
- Inventor: Osnat Bohana-Kashtan , Lior Ann Rosenberg Belmaker , Ofer Wiser
- Applicant: Cell Cure Neurosciences Ltd.
- Applicant Address: IL Jerusalem
- Assignee: CELL CURE NEUROSCIENCES LTD.
- Current Assignee: CELL CURE NEUROSCIENCES LTD.
- Current Assignee Address: IL Jerusalem
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- International Application: PCT/IL2015/051269 2015.12.30
- International Announcement: WO2016/108239A 2016.07.07
- Date entered country: 2017-06-23
- Main IPC: C12N5/079
- IPC: C12N5/079 ; A61K35/30

Abstract:
A population of human polygonal RPE cells is disclosed. At least 95% of the cells thereof co-express premelanosome protein (PMEL17) and cellular retinaldehyde binding protein (CRALBP), wherein the trans-epithelial electrical resistance of the cells is greater than 100 ohms. Methods of generating same are also disclosed.
Public/Granted literature
- US20180016553A1 RPE CELL POPULATIONS AND METHODS OF GENERATING SAME Public/Granted day:2018-01-18
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