Invention Grant
- Patent Title: Bacteriophage engineering via semi-synthesis
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Application No.: US16057416Application Date: 2018-08-07
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Publication No.: US11891630B2Publication Date: 2024-02-06
- Inventor: Kirsty A. McFarland , Miles T. Rogers , Connor McBrine , Jason W. Holder
- Applicant: The Charles Stark Draper Laboratory, Inc.
- Applicant Address: US MA Cambridge
- Assignee: The Charles Stark Draper Laboratory, Inc.
- Current Assignee: The Charles Stark Draper Laboratory, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Foley & Lardner LLP
- Main IPC: C12N7/02
- IPC: C12N7/02 ; C12N15/66 ; C12N15/10 ; C12N15/63
Abstract:
The present disclosure provides methods of generating recombinant bacteriophage genomes via semi-synthesis. Specifically, the present technology provides methods of integrating a heterologous nucleic acid sequence into a bacteriophage genome, and isolating recombinant bacteriophages that express the heterologous nucleic acid sequence.
Public/Granted literature
- US20190048325A1 BACTERIOPHAGE ENGINEERING VIA SEMI-SYNTHESIS Public/Granted day:2019-02-14
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