Invention Grant
- Patent Title: Optimization of yeast host cells for the production of heterologous proteins
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Application No.: US17277220Application Date: 2019-09-19
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Publication No.: US11891641B2Publication Date: 2024-02-06
- Inventor: Michelle Oeser , Janet Fisher , Aaron Argyros
- Applicant: Lallemand USA, Inc.
- Applicant Address: US NH Pembroke
- Assignee: Lallemand USA, Inc.
- Current Assignee: Lallemand USA, Inc.
- Current Assignee Address: US NH Pembroke
- Agency: Seed IP Law Group LLP
- International Application: PCT/IB2019/057944 2019.09.19
- International Announcement: WO2020/058915A 2020.03.26
- Date entered country: 2021-03-17
- Main IPC: C12N9/88
- IPC: C12N9/88 ; C12N9/00 ; C12N15/81
Abstract:
The present disclosure concerns yeast host cell especially suited for the expression of heterologous proteins, such as heterologous enzymes. The yeast host cell of the present disclosure exhibits an alteration in the cAMP signaling pathway which allows achieving increased heterologous protein yield and associated biological activity. The yeast host cell can also exhibit polyploidy.
Information query
