Invention Grant
- Patent Title: T cells with reduced surface fucosylation and methods of making and using the same
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Application No.: US16616928Application Date: 2018-06-05
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Publication No.: US11891644B2Publication Date: 2024-02-06
- Inventor: Nicole Okeley , Jessica Field , Shyra Gardai , Ryan Heiser
- Applicant: Seagen Inc.
- Applicant Address: US WA Bothell
- Assignee: Seagen Inc.
- Current Assignee: Seagen Inc.
- Current Assignee Address: US WA Bothell
- Agency: MORRISON & FOERSTER LLP
- International Application: PCT/US2018/036067 2018.06.05
- International Announcement: WO2018/226701A 2018.12.13
- Date entered country: 2019-11-25
- Main IPC: C12P21/00
- IPC: C12P21/00 ; A61P35/02 ; A61K31/7024 ; A61K35/17 ; C12N5/0783 ; A61K31/70
Abstract:
Methods of producing T cells having reduced surface fucosylation and use thereof in adoptive cell therapy, in particular, in cancer treatment are provided.
Public/Granted literature
- US20200149082A1 T CELLS WITH REDUCED SURFACE FUCOSYLATION AND METHODS OF MAKING AND USING THE SAME Public/Granted day:2020-05-14
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