A diaphragm pump assembly can include a pump drive chamber, a first pump diaphragm chamber, and a second pump diaphragm chamber. The assembly can include a pump motor configured to rotate a motor shaft extending into the pump drive chamber. The assembly can include a cam connected to the motor shaft and configured to rotate in response to rotation of the motor shaft. The assembly can include a drive yoke having a yoke frame and a yoke pocket having a first wall and a second wall parallel and opposite the first wall. First and second pistons can connect to the drive yoke and to first and second diaphragms, respectively. The diameter of the cam can be less than and within 5% the width of yoke pocket and the yoke can be configured to move the pistons along a straight line.