The present disclosure includes an inventory fulfillment system for managing information regarding pertaining to the inventory supply chain logistics and automation of medical items dispensed in conjunction with medical treatment of a patient at a medical facility, wherein the medical items are stored in a physical inventory space in the medical facility, wherein the medical items have radiofrequency tags attached thereto is disclosed herein. In some implementations, the inventory fulfillment system receives, dispenses, and manages, medical items that are provided by a multiplicity of suppliers, collects patients' payments. In some implementations, the inventory fulfillment system also includes assigning items to patients, updating inventory applications, insurance eligibility, patient estimation, and patient payment.