Examples are described for applying different settings for image capture to different portions of image data. For example, an image sensor can capture image data of a scene and can send the image data to an image signal processor (ISP) and a classification engine for processing. The classification engine can determine that a first object image region depicts a first category of object, and a second object image region depicts a second category of object. Different confidence regions of the image data can identify different degrees of confidence in the classifications. The ISP can generate an image by applying a different settings to the different portions of the image data. The different portions of the image data can be identified based on the object image regions and confidence regions.