Provided is a method of preparing an activated mineral solution, which includes steps of pulverizing granite and/or vermiculite into a powder by grinding, subjecting the powder to an electrolysis treatment, dissolving the powder in an aqueous ammonia solution and an acidic solution to prepare a mixed solution, emitting ultrasonic waves on the mixed solution, introducing microorganisms onto the mixed solution, and neutralizing the mixed solution, in which the mineral is selected from the group consisting of Fe, Mg, Al, Ti, K, Ca, Mn, Nb, P, Na, Zn, V, Cr, Ni, Si, B, Cu, Li, Ga, Co, Sr, In, Rb, Sb, Ta, Y, and combinations thereof.