Certain aspects of the present disclosure provide techniques for concurrently performing inferences using a machine learning model and optimizing parameters used in executing the machine learning model. An example method generally includes receiving a request to perform inferences on a data set using the machine learning model and performance metric targets for performance of the inferences. At least a first inference is performed on the data set using the machine learning model to meet a latency specified for generation of the first inference from receipt of the request. While performing the at least the first inference, operational parameters resulting in inference performance approaching the performance metric targets are identified based on the machine learning model and operational properties of the computing device. The identified operational parameters are applied to performance of subsequent inferences using the machine learning model.