Invention Grant
- Patent Title: Aminonapthoquinone compounds and pharmaceutical composition for blocking ubiquitination-proteasome system in diseases
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Application No.: US16740167Application Date: 2020-01-10
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Publication No.: US11919858B2Publication Date: 2024-03-05
- Inventor: Yun Yen , Jing-ping Liou , Shiow-lin Pan
- Applicant: Calgent Biotechnology Co., Ltd.
- Applicant Address: TW Taipei
- Assignee: Calgent Biotechnology Co., Ltd.
- Current Assignee: Calgent Biotechnology Co., Ltd.
- Current Assignee Address: TW Taipei
- Agency: Prosyla Group, PC
- The original application number of the division: US15746964
- Main IPC: A61K31/166
- IPC: A61K31/166 ; A61K31/167 ; A61K31/337 ; A61K31/4409 ; A61K31/475 ; A61K31/506 ; A61K31/593 ; A61K31/704 ; A61K33/24 ; A61P3/10 ; A61P25/28 ; A61P35/02 ; A61P37/00 ; C07D209/04 ; C07D213/74 ; C07D213/75 ; C07D213/76 ; C07D215/40 ; C07D215/42 ; C07D231/38 ; C07D235/30 ; C07D239/42 ; C07D241/04 ; C07D241/20 ; C07D277/42 ; C07D471/04 ; C07D487/04
Abstract:
The invention relates to compounds of formula (I)
with low cytotoxicity for blocking the ubiquitination-proteasome system in diseases. Accordingly, these compounds can be used in treatment of disorders including, but not limited to, cancers.
with low cytotoxicity for blocking the ubiquitination-proteasome system in diseases. Accordingly, these compounds can be used in treatment of disorders including, but not limited to, cancers.
Public/Granted literature
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