Invention Grant
- Patent Title: Isoform-selective anti-TGFβ antibodies and methods of use
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Application No.: US17205663Application Date: 2021-03-18
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Publication No.: US11919948B2Publication Date: 2024-03-05
- Inventor: Wei-Ching Liang , Joseph R. Arron , Daryle Depianto , Wendy Green Halpern , WeiYu Lin , Patrick J. Lupardus , Thirumalai Rajan Ramalingam , Dhaya Seshasayee , Tianhe Sun , Tulika Tyagi , Jia Wu , Yan Wu , Jian Ping Yin
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: GENENTECH, INC.
- Current Assignee: GENENTECH, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: HALEY GUILIANO LLP
- Agent Karen Mangasarian; Stacey W. Chung
- Main IPC: C07K16/22
- IPC: C07K16/22 ; A61K39/00 ; A61K39/395 ; A61P11/00 ; C07K16/46
Abstract:
The invention provides isoform-selective anti-TGFβ antibodies and methods of using the same. In particular, isoform-selective anti-TGFβ2, anti-TGFβ3, and anti-TGFβ2/3 monoclonal antibodies are provided, e.g., for the treatment of fibrosis and other TGFβ-related disorders.
Public/Granted literature
- US20210301005A1 ISOFORM-SELECTIVE ANTI-TGF-BETA ANTIBODIES AND METHODS OF USE Public/Granted day:2021-09-30
Information query
