Invention Grant
- Patent Title: Inhibitors of the interaction between CLEC14A and multimerin-2 for inhibition of angiogenesis
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Application No.: US16992497Application Date: 2020-08-13
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Publication No.: US11919959B2Publication Date: 2024-03-05
- Inventor: Roy Bicknell , Peter Noy , Kabir Ali Khan
- Applicant: Cancer Research Technology Limited
- Applicant Address: GB London
- Assignee: Cancer Research Technology Limited
- Current Assignee: Cancer Research Technology Limited
- Current Assignee Address: GB London
- Agency: McNeill Baur PLLC
- Priority: GB 01004 2015.01.21
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/30 ; A61P35/00 ; G01N33/50 ; A61K39/00

Abstract:
The invention provides a method of inhibiting angiogenesis in an individual, the method comprising administering to the individual an agent that inhibits the interaction between CLEC14A and MMRN2. The inhibitor may be an antibody, a polypeptide, a peptide, a polynucleotide, a peptidomimetic, a natural product, a carbohydrate, an aptamer or a small molecule.
Public/Granted literature
- US20210070867A1 Inhibitors of the Interaction Between CLEC14A and Multimerin-2 for Inhibition of Angiogenesis Public/Granted day:2021-03-11
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