Invention Grant
- Patent Title: Carborhodamine compounds and methods of preparation thereof
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Application No.: US18073929Application Date: 2022-12-02
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Publication No.: US11920040B2Publication Date: 2024-03-05
- Inventor: Eugeny A. Lukhtanov
- Applicant: ELITECHGROUP MDX LLC
- Applicant Address: US WA Bothell
- Assignee: ELITECHGROUP MDX LLC
- Current Assignee: ELITECHGROUP MDX LLC
- Current Assignee Address: US WA Bothell
- Agency: Jackson Walker LLP
- The original application number of the division: US17482611 2021.09.23
- Main IPC: C09B11/24
- IPC: C09B11/24 ; C12N9/12 ; C12Q1/68 ; C12Q1/6876 ; G01N21/64

Abstract:
The carborhodamine dyes disclosed herein are novel reagents suitable for automated incorporation of carborhodamine dyes into oligonucleotides that can be used in detection methods for nucleic acid targets. This disclosure provides an efficient and simple process for the preparation of carborhodamine compounds and introduces previously unknown reagents for the automated synthesis of oligonucleotide-carborhodamine conjugates.
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