Invention Grant
- Patent Title: Methods for expanding hematopoietic stem cells using revitalized mesenchymal stem cells
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Application No.: US16620839Application Date: 2018-06-07
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Publication No.: US11920159B2Publication Date: 2024-03-05
- Inventor: Paul S. Frenette , Fumio Nakahara
- Applicant: Albert Einstein College of Medicine
- Applicant Address: US NY Bronx
- Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE
- Current Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE
- Current Assignee Address: US NY Bronx
- Agency: Perkins Coie LLP
- International Application: PCT/US2018/036408 2018.06.07
- International Announcement: WO2018/226926A 2018.12.13
- Date entered country: 2019-12-09
- Main IPC: C12N5/0775
- IPC: C12N5/0775 ; A61K35/28 ; C12N15/86
Abstract:
A method for revitalizing mesenchymal stem cells (MSC) maintained in culture by transducing the MSC with vectors encoding a specific gene combination, as well as methods of use of MSC so revitalized in co-culturing hematopoietic stem cells.
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