- Patent Title: Fatty acid derivatives for treating non-alcoholic steatohepatitis
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Application No.: US16769659Application Date: 2018-12-05
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Publication No.: US11925614B2Publication Date: 2024-03-12
- Inventor: Hilde Hermansen Steineger , David Alan Fraser , Tore Skjæret
- Applicant: BASF AS
- Applicant Address: NO Oslo
- Assignee: BASF AS
- Current Assignee: BASF AS
- Current Assignee Address: NO Oslo
- Agency: FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER, LLP
- Priority: NO 171944 2017.12.06 NO 171945 2017.12.06
- International Application: PCT/IB2018/001459 2018.12.05
- International Announcement: WO2019/111048A 2019.06.13
- Date entered country: 2020-06-04
- Main IPC: A61K31/202
- IPC: A61K31/202 ; A61K9/00 ; A61K45/06 ; A61P1/16

Abstract:
The present disclosure provides a compound for use in therapeutic and/or prophylactic treatment of non-alcoholic steatohepatitis (NASH) and/or alcoholic steatohepatitis (ASH). The compound for use according to the invention, is an unsaturated fatty acid with an oxygen incorporated in the β-position, and further comprising an α-substituent. More particularly, the invention provides a compound for use in treatment of NASH and/or ASH, and a method using this, wherein the compound is of Formula (II), wherein RI, R2, R3, X, and Y are as defined in the specification; and wherein this compound may be administered alone or in combination with an additional active agent.
Public/Granted literature
- US20210177794A1 FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS Public/Granted day:2021-06-17
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