Invention Grant
- Patent Title: KRas G12C inhibitors
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Application No.: US17053273Application Date: 2019-05-06
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Publication No.: US11932633B2Publication Date: 2024-03-19
- Inventor: Matthew Arnold Marx , Matthew Randolph Lee , James F. Blake , Mark Joseph Chicarelli , Jay Bradford Fell , John P. Fischer , Erik James Hicken , Pavel Savechenkov , Tony Tang , Guy P. A. Vigers , Henry J. Zecca
- Applicant: Mirati Therapeutics, Inc. , Array BioPharma, Inc.
- Applicant Address: US CA San Diego
- Assignee: Mirati Therapeutics, Inc.,Array Biopharma Inc.
- Current Assignee: Mirati Therapeutics, Inc.,Array Biopharma Inc.
- Current Assignee Address: US CA San Diego; US CO Boulder
- Agency: Wood, Phillips, Katz, Clark & Mortimer
- International Application: PCT/US2019/030896 2019.05.06
- International Announcement: WO2019/217307A 2019.11.14
- Date entered country: 2020-11-05
- Main IPC: C07D413/06
- IPC: C07D413/06 ; A61P35/00 ; C07D413/04 ; C07D413/14 ; C07D417/14
Abstract:
The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
Public/Granted literature
- US20210380570A1 KRAS G12C INHIBITORS Public/Granted day:2021-12-09
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