Invention Grant
- Patent Title: Modified cytomegalovirus proteins and stabilized complexes
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Application No.: US17223207Application Date: 2021-04-06
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Publication No.: US11932669B2Publication Date: 2024-03-19
- Inventor: Enrico Malito , Matthew James Bottomley , Andrea Carfi , Sumana Chandramouli , Kate Luisi
- Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
- Applicant Address: BE Rixensart
- Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee Address: BE Rixensart
- Main IPC: C07K14/045
- IPC: C07K14/045 ; A61K38/00 ; A61K39/245
Abstract:
Described are mutant human cytomegalovirus (HCMV) pentamer complex polypeptides, methods of making them, and their use in HCMV protein complexes and compositions. In particular, the use of the modified HCMV polypeptides to stabilize HCMV complexes or unmask a pentamer epitope is described.
Public/Granted literature
- US20210277067A1 MODIFIED CYTOMEGALOVIRUS PROTEINS AND STABILIZED COMPLEXES Public/Granted day:2021-09-09
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