Invention Grant
- Patent Title: Antibodies specific to glycosylated PD-L1 and methods of use thereof
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Application No.: US17097817Application Date: 2020-11-13
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Publication No.: US11933786B2Publication Date: 2024-03-19
- Inventor: Stephen S. Yoo , Ezra M. Chung , Yong-Soo Kim , Mien-Chie Hung , Chia-Wei Li , Seung-Oe Lim
- Applicant: STCUBE, INC. , BOARD OF REGENTS, THE UNIVERSITY OF TEXAS
- Applicant Address: KR TX Seoul
- Assignee: STCUBE, INC.,BOARD OF REGENTS, THE UNIVERSITY OF TEXAS
- Current Assignee: STCUBE, INC.,BOARD OF REGENTS, THE UNIVERSITY OF TEXAS
- Current Assignee Address: KR Seoul; US TX Austin
- Agency: Ballard Spahr, LLP
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07K16/28 ; C07K16/30 ; G01N33/574
Abstract:
Antibodies that selectively bind to glycosylated PD-1 relative to unglycosylated PD-1 are provided. In some aspects, PD-1 polypeptides comprising glycosylated amino acid positions are also provided. Methods for making and using such antibodies and polypeptides (e.g., for the treatment of cancer) are also provided.
Public/Granted literature
- US20220276252A9 ANTIBODIES SPECIFIC TO GLYCOSYLATED PD-L1 AND METHODS OF USE THEREOF Public/Granted day:2022-09-01
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