Methods and systems are provided for using a user's line of sight (LOS) and/or gaze direction to enhance displayed data and control various displays and instruments. The user's LOS is tracked, corresponding element(s) in a scene at which the user gazes are identified, e.g., in a database, and respective displayed data are enhanced or otherwise manipulated with respect to the identified element(s). The database may be multilayered and may comprise data layers which are conformal to a scene representation. Users may also select, using their LOS, among multiple layers of information and among multiple displayed parts to enhance or attenuate respective layers or parts. Designated elements may be real-world elements, displayed elements or instruments in the operational surroundings of the user. Identification of elements at which LOSs of multiple users are aimed at may be used for exchange of information among the users.