Invention Grant
- Patent Title: Genetically modified MSC and therapeutic methods
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Application No.: US17168645Application Date: 2021-02-05
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Publication No.: US11939591B2Publication Date: 2024-03-26
- Inventor: Jan Nolta , Karen Pepper , Fernando Fierro , Gerhard Bauer
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Foley & Lardner LLP
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A61K48/00 ; C12N15/86
Abstract:
This disclosure relates to vectors, isolated cells, compositions, and methods for the treatment of critical limb ischemia and associated disorders. One aspect of the disclosure relates to a vector comprising a nucleic acid encoding a 165A isoform VEGF protein and a promoter that regulates expression of the nucleic acid encoding the VEGF.
Public/Granted literature
- US20220002748A1 GENETICALLY MODIFIED MSC AND THERAPEUTIC METHODS Public/Granted day:2022-01-06
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